for-gestational-age and musculoskeletal malforma-
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چکیده
and FT4. Pregnant women were classified by hormone status into percentile categories based on laboratory assay and were compared accordingly. The authors found that OH was associated with increased fetal loss, low birth weight and congenital circulation system malformations. SCH was associated with increased fetal distress, preterm delivery, poor vision development and neurodevelopmental delay. Isolated hyperthyroxinemia was related to fetal distress, smallfor-gestational-age and musculoskeletal malformations. Isolated hyperthyroxinemia was associated with spontaneous abortion. Finally, clinical hyperthyroidism was associated with hearing dysplasia. The conclusion is that thyroid dysfunction in the first 20 wks of pregnancy may result in fetal loss and dysplasia and some congenital malformations.
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